Tag: ERCC1

High Density Protein Arrays for Antibody Validation

A recent paper in BMC Biotechnology by D. Ma et. al of Origene describes the use of high density protein arrays to test the specificity, or lack thereof, for antibodies used for immunoassay diagnostics. The antibody 8F1 is  commonly used in immunohistochemistry assays to detect ERCC1 protein, a biomarker for testing the efficacy of cisplatin-based chemotherapy used in non-small lung … Continued