IMAGING AND MICROSCOPY
Grace Bio-Labs solutions for imaging and microscopy are designed to expedite cells and tissue staining and fixing. Constructed of high-quality bio-compatible materials and manufactured with minimal particle contamination, they offer an economical alternative to expensive re-usable systems. We offer a wide range of design alternatives for control of environmental conditions and to economize reagent consumption.
Grace Bio-Labs imaging spacers are ideally suited for:
- cell/tissue staining
- high-resolution microscopy
- immunohistochemistry
- live-cell time-lapse
Contact us if you have a unique application that requires an entirely new design.
Imaging spacers are ultra-thin adhesive spacers which peel-and-stick to coverglass or microscope slides to confine specimens without compression. Layer multiple spacers to custom build chambers to any depth desired. Thin, double-sided adhesive spacers confine specimens without compression. For high resolution microscopy, sandwich specimen and spacer between two No. 0 coverglass. Imaging spacers can be fabricated in different material and thickness for specific applications. The adhesive, also used to make Wound Splints, HybriWell and SecureSeal incubation chambers, is now available in sheets that may be purchased in a single layer thickness or prepared in multiple layers for your convenience.
CoverWell ™ imaging chambers are designed to stabilize and support thick and free-floating specimens for confocal microscopy and imaging applications. The reusable press-to-seal silicone chambers form removable enclosures for repeat staining or specimen re-positioning.
Silicone Isolators allow researchers to isolate specimens using removable hydrophobic barriers. They may be used to isolate cells grown in culture dishes or separate multiple specimens affixed to microscope slides. Isolators are available in red silicone thickness 0.5 to 2.5mm pre-cut or as sheet material with or without secure seal clean adhesive on one or both surfaces. Nonadhesive isolators are autoclavable and reusable.Silicone Isolators™ remain sealed to smooth surfaces during washing steps. Where additional sealing is required, SecureSeal™ adhesive on one or both surfaces is recommended.
CoverWell ™ perfusion press-to-seal covers form water-tight, multiwell cell incubation or cytochemistry chambers when pressed to coverslips or microscope slides. Reagents can be quickly added and removed through dual access ports without disturbing or cross-contaminating specimens. Chambers are available in five chamber configurations allowing up to eight different specimens or analytical tests on one coverglass.
FastWells™ are sticky, flexible silicone gaskets that form hydrophobic reagent barriers around specimens without messy adhesives or special slides. Gaskets may be stacked to increase depth and volume. FastWell™ Reagent Barriers provide rapid isolation of cells and tissues on slides or coverslips for antibody incubations. The barriers remain sealed during agitated washing steps, preventing reagents from spilling when shaken or rocked. FastWells™ peel off quickly and cleanly, leaving no residue to interfere with specimen cover-slipping. They can be washed, autoclaved and reused. The barriers can also be sealed to form incubation chambers using flexible HybriSlip™ covers.
