SecureSeal™ Frame

SecureSeal™ Frames are comprised of a non-cytotoxic, nuclease free, double-sided adhesive designed to form leak-proof / vapor-proof incubation chambers on microscope slides. Sealed chambers containing reagents withstand temperatures up to 97oC and are ideally suited for applications such as in situ PCR and hybridization incubations requiring denaturation steps. Frames are 0.25mm thick and available in multiple sizes.

Components may be sterilized by autoclaving, UV-treatment, or immersion in Isopropyl Alcohol. Reaction mixtures may be recovered from the chamber after incubation by puncturing the flexible plastic cover using a hypodermic needle and withdrawing solution using a syringe or a pipette. Frames are easily removed from glass slides without leaving a residue.

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Property

SecureSeal™ Frames

Covers

25uL

65uL

125uL

SecureSeal™ Frame only

620101

620103

620105

Inner Dimensions

10 x 10

15 x 16

17 x 28

Outer Dimensions

20 x 20

25 x 25

28 x 36

25 x 46

Thickness

0.25mm

SecureSeal™ Frame with cover

620102

620104

620106

Cover only

Application Areas

Cell Biology

Molecular Biology

Neuroscience

Cancer Research

Features and Benefits

  • Designed for use with standard microscope slides
  • Exceptional leak-proof performance
  • Non-cytotoxic adhesive
  • Gas tight sealing prevents reagent loss due to evaporation
  • Withstands temperatures of 97° C
  • Sterilization by autoclaving or by UV irradiation
  • Removes cleanly without leaving residue
  • Rigid coverslips for ease of handling and uniform hybridizations
  • Thickness of Frames: 0.25 mm
  • Packs are available for Frames Only (Coverslips sold separately) or as Sets of Frames which include Coverslips

Applications

  • In-situ PCR
  • Microarray Hybridizations
  • In-situ Hybridization

Fields of Study

  • Cell Biology
  • Molecular Biology
  • Neuroscience
  • Cancer Research

References

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