Category: ProCrystal Protein Crystallization Covers

Portable UV holographic microscope for high-contrast protein crystal imaging

Methods and materials that facilitate the distinction between salt and protein crystals are extremely valuable to crystallographers. The rapid identification of promising crystallization conditions helps to streamline a process that is otherwise largely unpredictable. A commonly used approached is based on the properties of protein crystals to emit fluorescence when excited with UV light. It … Continued

Tryptophan Fluorescence identification of protein crystals

Protein crystallization is a highly demanding and time-consuming technique that constitutes a significant time constraint for basic research applications. Robotics allow high-throughput screening and optimization of crystallization conditions while minimizing the amount of protein necessary to conduct initial testing.  However, the ability to distinguish a protein crystal from salt or amorphous material has not been … Continued