Protein crystallization is a key assay for structural studies of proteins. The protocols for crystallization of protein are challenging due to the stringent requirement for pure samples and control of environmental conditions during the crystallization process. Vapor diffusion using hanging drop is a preferred method for obtaining quality crystals with…
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Grace Bio-Labs microarray surface chemistry is based on the well-known protein-binding properties of nitrocellulose. A range of different formulations have…
Antigen-Capture Assay; Antibody Capture Assay; Coronavirus Antigen Array; Epitope-mapping; Biomarker Discovery and Validation; Immunogen Discovery;
Epoxy Microarray Slides provide a uniform substrate for a variety of DNA/RNA-based diagnostic applications.
DNA/Oligonucleotide Microarray ; microRNA Microarray ; Single Nucleotide Polymorphism (SNP) Analysis ; Gene Expression Profiling;
Grace Bio-Labs microarray regents have been specifically formulated to achieve the full potential of porous nitrocellulose, accelerating experimental design and…
Antigen-Capture Assay ; Antibody Capture Assay; RPPA- Reverse Phase Protein ; Microarray Laser micro-dissection; RRPA Epitope-mapping ; Biomarker Discovery and Validation; Immunogen Discovery;
Photostable nanoparticles arrayed on glass slides for calibration of fluorescence imaging systems and quantitative analysis.
Calibration of Microarray Scanners ; Quantitative Microarray Analyses Microscope Focal Plane Adjustment; Microscope Focal Plane Adjustment;
ProPlate® re-usable, multi-well chambers are available in a wide variety of formats to fit standard 1 x 25 x 75…
Microarray ; Hybridization and Incubation; ELISA; PCR and NGS;
CoverWell™ incubation chambers are reusable, easy to apply chambers that attach without the use of adhesive. CoverWells™ enclose a large…
Reverse Transfection Microarray; DNA Microarray; In-situ hybridization; Immunohistochemistry;
Silicone Isolators allow researchers to isolate specimens using removable hydrophobic barriers. They may be used to isolate cells grown in…
SecureSeal™ Hybridization Chambers are thin, silicone-gasketed chambers providing optimal surface-to-volume fluid dynamics for hybridization assays on large or multiple specimens…
HybriWell™ Sealing System bonds securely to a microscope slide surface in seconds to confine small reagent volumes with samples and…
Hybridization and incubation Seals ad Chambers from Grace Bio-Labs are ideally suited for in situ-hybridization assays. The adhesive seal of…
In-situ hybridization ; Microarrays; Fluorescence In situ Hybridization (FISH); FRET (Fluorescence Resonance Energy Transfer);
FastWells™ are sticky, flexible silicone gaskets that form hydrophobic reagent barriers around specimens without messy adhesives or special slides. Gaskets may…
FlexWell™ incubation chamber silicone gaskets form wells on slides using clean release adhesive to isolate up to 16 specimens per…
HybriSlips™ are rigid, light-weight, thin plastic coverslips that minimize friction and facilitate uniform reagent distribution during incubation steps which require…
ProPlates® were specifically designed to enable automated robotic liquid handling. Two main configurations are available: The ProPlate® Microtiter Plate is comprised…
Proteomics; Protein Microarrays; Protein expression analysis; Antibody profiling ; cDNA and oligonucleotide arrays;
Silicone isolator™ sheet material allows researchers to create their own removable hydrophobic barriers to isolate specimens. Where additional sealing is…
Protein and DNA arrays ; Immunohistochemistry; Fluorescence In situ Hybridization (FISH) ; Biopolymers and hydrogel formulation ; Cryogenic-transmission electron microscopy (Cryo-TEM) ; Microwave crystallization ; Ultra-small-angle X-ray scattering (USAXS) ; Tissue ingeneering; Live cell lithography” (LCL);
Grace Bio-Labs microscopy reagents are manufactured in ISO-certified facilities to ensure the highest quality and consistency.
Imaging spacers are ultra-thin adhesive spacers which peel-and-stick to coverglass or microscope slides to confine specimens without compression. Layer multiple…
Imaging; Microscopy; High-temperature single-molecule kinetic analysis; Anti‐Stokes Raman scattering microscopy;
CoverWell ™ imaging chambers are designed to stabilize and support thick and free-floating specimens for confocal microscopy and imaging applications.…
Confocal microscopy ; Imaging ; Tissue and Cell staining ; High Resolution Microscopy ; Live-cell imaging ;
CoverWell ™ perfusion press-to-seal covers form water-tight, multiwell cell incubation or cytochemistry chambers when pressed to coverslips or microscope slides.…
Single molecule spectroscopy ; Live-cell imaging ; Microscoscopy ;
FastWells™ are sticky, flexible silicone gaskets that form hydrophobic reagent barriers around specimens without messy adhesives or special slides. Gaskets may…
Microscopy ; Fluorescence In situ Hybridization (FISH) ; Single-molecule fluorescence analysis ; Immunohistochemistry ;
MutliSlip™ inserts with 8 (18mm x 18mm) or 15 (12mm x 12mm) No. 1.5 German glass coverglass per insert are…
High resolution microscopy; Fluorescent imaging; Immunohistochemistry ; Cell Culture;
These adhesive sheets are made using the same SecureSeal™ adhesive as is used to make HybriWell™ and SecureSeal™ Incubation Chambers. Thin,…
Imaging ; Tissue and Cell staining ; High Resolution Microscopy;
SecureSlip™ Silicone Supported Coverglass is affixed to a thin microscopically transparent silicone base which secures it to culture vessels by…
Imaging seals and chambers from Grace Bio-Labs offer a selection of tools for cell/tissue staining for high quality results in…
Tissue and Cell staining; High Resolution Microscopy; Live-cell imaging;
Grace Bio-Labs microscopy reagents are manufactured in ISO-certified facilities to ensure the highest quality and consistency.
CultureWell- removable chamber slide allows the cultivation and analysis of cells directly on a borosilicate microscope slide.
Fluorescence microscopy ; Confocal microscopy ; Cell differentiation and transfection; Immunohistochemistry ; Immunofluorescence; Immunostaining; Tissue and cell staining ; Fluorescence Resonance Energy Transfer (FRET) Microscopy;
CultureWell™ chambered coverglass products consist of removable and reusable, non-cytotoxic silicone gaskets secured to number 1.5 German coverglass. Chambered coverglass…
Cell Culture ; Fluorescence applications ; In-situ hybridization ; Immunostaining ;
CS16 CultureWell™ removable chambered coverglass is a 16-well chambered coverglass cell culture vessel, with 2 x 8 format with standard…
Cell Culture; Fluorescence applications; In-situ hybridization; Immunostaining ;
Each CultureWell™ coverglass insert is comprised of four chambered coverglass, assembled in a disposable frame placed in a standard 86mm…
High resolution microscopy ; Fluorescent imaging ; Immunohistochemistry;
Gaskets are ideal for forming wells on glass microscope slides or in polystyrene dishes. Gaskets are non-sterile and may be…
Cell Culture; High resolution microscopy; Fluorescent imaging ; Immunohistochemistry;
CultureWell™ clear silicone sheet material allows researchers to create their own removable hydrophobic barriers to isolate specimens. They may be…
Cell Culture; High resolution microscopy ; Fluorescent imaging; Immunohistochemistry;
MutliSlip™ inserts with 8 (18mm x 18mm) or 15 (12mm x 12mm) No. 1.5 German glass coverglass per insert are…
SecureSlip™ Silicone Supported Coverglass is affixed to a thin microscopically transparent silicone base which secures it to culture vessels by…
CultureWell™ NON Removable Chambered Coverglass, 16 Well, No. 1.5 German borosilicate Coverglass. Product consists of cell culture vessels, with a…
Cell Culture ; Fluorescence applications; Small volume incubation ; Immunostaining;
Wound splints are constructed of silicone and include suture sites for increased precision in affixing on or within an animal…
Silicone isolator™ sheet material allows researchers to create their own removable hydrophobic barriers to isolate specimens. Where additional sealing is…
Protein and DNA arrays ; Immunohistochemistry ; Fluorescence In-situ Hybridization (FISH) ; Biopolymers and hydrogel formulation; Cryogenic-transmission electron microscopy (Cryo-TEM) ; X-ray scattering ; Microwave crystallization ; Ultra-small-angle X-ray scattering (USAXS) ; Tissue engineering Live cell lithography (LCL);
CultureWell™ clear silicone sheet material allows researchers to create their own removable hydrophobic barriers to isolate specimens. They may be…
Lorem Ipsum ; Lorem Ipsum; Lorem Ipsum;
HybriWell™ hybridization chambers are the ideal tool for conserving precious or costly reagents in imaging experiments. HybriWells™ are inexpensive, disposable devices that create a chamber whose ports allow liquid exchange via microfluidic passive pumping [2], as demonstrated in this video: Seitz et, al. recently applied the method to develop and test fluorescence-based genetically-encoded biosensors to study … Continued
A simple fluidic design integrates directly into standard cell culture and biochemical assays as a part of new experimental methods published recently. The fluidic design used single channel or T-shaped flow chambers and a syringe pump to effectively culture and assay cells in a continuous gradient of conditions. These methods simultaneously expand experimental capability and … Continued
One of the best aspects of working with Grace Bio-Labs and the in-situ hybridization and chambering devices is the opportunity to learn some novel applications which are developed by the users of these tools. Sometimes our customers can teach us a few things about applications for our products!As recently as this summer, a very interesting … Continued
SecureSeal Hybridization Chambers were originally developed to perform hybridizations on specimens affixed to glass slides or to perform microarray incubations with limited volumes (SecureSeal References). The peel- and- stick adhesive chambers can be created in various sizes to accommodate different samples, including partial membrane blots from protein mini-gels (shown here). Recently we have investigated the … Continued
Microarray technology was first exploited with genomic analysis of DNA sequences. This technology still forms a robust platform for biomarker discovery and comparative genomics. However, while genomics sheds light on the biological potential, a recent review in Science Signaling points out that “protein does the heavy lifting in the cell, and neither DNA nor RNA says much … Continued
